Gabapentinoids are used for neuropathic pain including postherpetic neuralgia. Which of the following best describes their commonly observed side effects and a renal consideration?

Gabapentinoids are used for neuropathic pain including postherpetic neuralgia. Which of the following best describes their commonly observed side effects and a renal consideration?

• A. Effective for neuropathic pain including postherpetic neuralgia; common side effects include dizziness, somnolence, peripheral edema; adjust for renal impairment
• B. They are primarily NSAIDs with minimal side effects
• C. They are short-acting opioids with a high risk of respiratory depression
• D. They cure postherpetic neuralgia with no adverse effects

Answer: (B)